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Compatible, build-to-spec single-use fluid paths for automated crossflow filtration skids.
BPSSU builds single-use TFF fluid paths to your specification as a compatible second source for automated crossflow skids. From individual line kits to complete flow-path sets, assemblies can provide cost relief, supply-chain redundancy, and configurations that may not be available through the OEM catalog—while your skid, membrane, and process remain unchanged.
A Second Source Without Changing Your Process
Automated TFF skids rely on single-use fluid paths that are consumed with each batch. These paths can include tubing lines, pump chambers, valves, filtration, reservoirs, and supporting connection components.
BPSSU builds these fluid paths to customer specifications as a compatible second-source option. The goal is straightforward: BPSSU builds the disposable path while your existing skid, membrane, and process stay unchanged.
Assemblies can be supplied as individual line kits or as a complete TFF flow-path set.
Access detailed product information, technical specifications, and supporting resources.
Detailed information about this product, features, applications, and technical specifications.
What is a single-use TFF flow path assembly?
A TFF flow path assembly is a configured disposable fluid path used with tangential flow filtration systems. It can incorporate feed, retentate, permeate, buffer, and other process lines into a ready-to-integrate assembly.
Can BPSSU build TFF flow paths for existing equipment?
Yes. BPSSU can develop build-to-spec TFF assemblies around existing equipment and process requirements, including systems such as Repligen KrosFlo® and Sartorius Sartoflow®.
What components can be included in a TFF flow path?
Depending on the process, TFF assemblies can incorporate tubing, pump chambers, valves, filters, connectors, reservoirs, manifolds, and other components required by the fluid path.
Compatible Second Source
Introduce an additional source for critical TFF disposables without changing the underlying skid or process.
Individual Lines or Complete Sets
Source only the lines you need or develop an entire single-use flow path.
Supply-Chain Redundancy
Add flexibility to sourcing critical consumables and reduce dependence on a single supplier.
Build-to-Spec Configurations
Develop configurations around your actual equipment and process rather than being limited exclusively to catalog options.
Integrated Components
Pump chambers, tubing, valves, filtration, connections, disconnectors, and reservoirs can be incorporated into the flow path.
BioProcess Supplies (BPSSU) provides single-use bioprocess solutions designed to support your process from R&D and development through clinical and commercial manufacturing. Our team works directly with customers to develop practical, ready-to-integrate solutions using quality components and configurations built around your specific requirements.
Assemblies are manufactured in our ISO 7 classified cleanroom with full traceability and supporting documentation. As a smaller, more nimble supplier, BPSSU combines responsive service, direct communication, and flexible manufacturing to help keep your process moving.
Pump, filter, distribution, and fill container are all integrated into a single closed-system disposable. No coordinating across multiple suppliers, no in-house assembly steps.
From bulk drug substance to final fill container, every connection is sterile or weldable with no open transfers, no contamination risk.
We integrate with whatever fill equipment you have— pump type, container format, filter requirements all matched to your process.
Every assembly ships gamma-irradiated and individually packaged. Drop into your fill operation with no further sterilization.
Most fill component suppliers sell you the tubing, the filter, and the container as separate items—leaving in-house assembly to you. We build the entire integrated assembly so it arrives ready to install.
Pump-grade tubing, sterilizing-grade filters, sterile connectors, manifolds, bottles, bags—all from BPSSU. We design the assembly using components we already build for upstream operations.
Final-Fill is the most quality-critical step in your process. Every assembly is built to the same standards as our upstream and downstream products.
Our team is ready to help you build the right solution.
